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Article: NAD+ and the Brain: How This Molecule Supports Cognitive Longevity

NAD+ and the Brain: How This Molecule Supports Cognitive Longevity

NAD+ and the Brain: How This Molecule Supports Cognitive Longevity

We've delved into how NAD+ affects cellular longevity and metabolic health, but what about its role in brain function? Research increasingly suggests that NAD+ has significant neuroprotective effects. In this blog, we'll examine how NAD+ supports brain health and may even offer a pathway to cognitive longevity.

NAD+ and Cognitive Functions

Neurotransmitter Regulation

NAD+ is essential for producing neurotransmitters, the chemicals that enable neurons to communicate with each other, thus supporting cognitive functions like memory and attention.

Mitochondrial Health

Mitochondria are the energy powerhouses of cells, and their well-being is crucial for brain health. NAD+ plays a role in maintaining mitochondrial function, which has significant implications for preventing neurodegenerative diseases.

The Science Behind It

Animal Studies

Studies in rodents have shown that increasing NAD+ levels could mitigate age-associated cognitive decline and improve learning and memory performance.

Human Trials

Although limited, some clinical trials have examined the cognitive benefits of NAD+ supplementation, with preliminary results showing potential in improving mental clarity and focus.

NAD+ and Neurodegenerative Diseases

Alzheimer's Disease

Research indicates that NAD+ may reduce the severity of Alzheimer’s symptoms by enhancing energy metabolism and reducing oxidative stress in brain cells.

Parkinson's Disease

Similarly, NAD+ has been implicated in protecting dopamine-producing neurons, which are typically affected in Parkinson's disease.


NAD+ appears to offer substantial neuroprotective benefits, ranging from improved cognitive function to potential roles in combating neurodegenerative diseases. As with many areas in the NAD+ landscape, more research is needed, particularly human trials, to confirm these promising findings fully.



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